──【CC-BY-SA 4.0】Turner, M. (2014). ¹⁾

• Sackett が提唱した EBM の 5 steps の原文²⁾は以下の通り

The practice of evidence-based medicine is a process of life-long, self-directed learning in which caring for our own patients creates the need for clinically important information about diagnosis, prognosis, therapy, and other clinical and health care issues, and in which we (1) convert these information needs into answerable questions; (2) track down, with maximum efficiency, the best evidence with which to answer them (whether from the clinical examination, the diagnostic laboratory from research evidence, or other sources); (3) critically appraise that evidence for its validity (closeness to the truth) and usefulness (clincial applicability); (4) integrate this appraisal with our clinical expertise and apply it in practice; and (5) evaluate our performance.

• 1996年の「EBMとは何か」論文³⁾において，Sackett 氏が「エビデンスは患者の臨床状態や境遇，嗜好などと合致するかも含めて適用すべきかどうか決めるものである」ことを明記していることを踏まえ（＊）部分を強調した

External clinical evidence can inform, but can never replace, individual clinical expertise, and it is this expertise that decides wheter the external evidence applies to the individual patient at all and, if so, how it should be integrated into clinical decision.Similarly, any external guideline must be integrated with individual clinical expertise in deciding whether and how it matches the patient's clinical state, predicament, and preferences, and thus　whether it should be applied.

• 専門家の臨床経験は EBP（Evidence-Based Practice）の定義の一部であるが，Health professionals は，意思決定のために臨床経験のみに頼るのではなく，臨床経験とエビデンスに基づく情報とを併用する必要がある